The company has been family-run since it was founded in 1860 and is currently in the hands of fourth and fifth generation Robinsons.
It has a long history of selling mammoth vegetable seed and has been responsible for numerous firsts.
Partner Susan Robinson said the company would take time to reflect on the milestone.
"One year can start to run into another but I think it's good to stop and think about this one and say ‘wow, 150 years, we have to mark this somehow.'"
The RHS Chelsea Flower Show will kick off a year of celebration as the company will put on a special display of award cards and trophies dating back as far as the late 1800s.
Similar exhibits will be held at Gardeners' World Live and the Malvern Autumn Show but the centrepiece of the celebrations will be Tatton Park.
In a special exhibition the company will devote one third of its display to history: exhibiting an old tractor, old tools and horticultural diaries kept by various members of the family since it was founded.
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