Extensive landscape and cycle routes snake around new homes for the college’s key workers such as trainee doctors, researchers and lecturers.
The masterplan, by PLP Architecture and Aukett Fitzroy Robinson, included public access to a new open green space at the heart of the development.
A spokesman for the project said: "A new London square the size of Soho Square will open up a site that has been closed off to the public for many decades."
Project director John Anderson, said designers worked with residents, the Greater London Authority and Hammersmith & Fulham and Kensington & Chelsea local authorities.
This forms the second phase of redevelopment of the world-famous college site. First phase is under construction to house 600 postgraduates and is due to end this July.