Matthew and Suzie Jones discovered knotweed growing in their house and its value was subsequently cut in half from £300,000.
Speaking to BBC One’s Inside Out programme, Suzie Jones said: "We were told we’d have to have our house torn down. You don’t expect that when you’ve just bought a brand new home."
Natalie Waterworth told the programme that she was about to buy her first home when her bank was made aware of Japanese knotweed on the premises and it withdrew the mortgage.
She said: "The knotweed was about 90 feet from the house but in a few weeks it had advanced 60 feet, and then 30. I wouldn’t try to buy a property that has Japanese knotweed — it’s doomed to fail."
Sue Anderson, from the Council of Mortgage Lenders, said: "It’s an evolving situation. Knotweed has gained so much awareness it can make a prospective property unpopular to buyers. A lender has to consider all these factors."