Head gardener and chief executive Fergus Garrett has extended the invitation to all growers for what he hopes will become an annual event.
He said: "The weekend will be plant-driven with the aim of getting specialists, growers and plantsmen together."
Talks will be held by nurserymen throughout the weekend, offering an insight into their plants.
Several UK and overseas nurseries have already signed up, including:
Hessenhof from the Netherlands, Usual & Unusual Plants, Cotswold Garden Flowers, Phoenix Plants, Marchants Plants, Tony Dickerson, Special Plants; Van Pouke from Belgium, Great Comp and Ewald Hugin from Germany
Some of the profits will go toward an annual travel scholarship for horticultural students.
Price entry for the Plant Fair will be included in the entry ticket to Great Dixter GardensFor more information contact Linda Jones firstname.lastname@example.org 01797 254048