A tender has now been issued to appoint a design team to help deliver improvements at Aldgate, White-chapel and Mile End as part of the High Street 2012 programme.
The aim is to improve the high street, which connects Aldgate and the City of London to Stratford and the Olympic Park. The area is part of the Olympic and Paralympic marathon route.
A Tower Hamlets representative commented: "Although the high street runs through some of the most disadvantaged neighbourhoods in the capital, it also passes some of the most culturally diverse and historically rich areas of London."
The borough council has commissioned a High Street 2012 Vision Study along with Design for London, Newham Council, Transport for London, English Heritage and the London Thames Gateway Development Corporation.
The design team appointed will help take forward the delivery of the £4.6m project, which includes planting, improved park entrances and landscaping as well as lighting, street furniture and footpath landscaping.
The work is being accelerated in an attempt to provide a boost to the construction sector and must be completed by March 2012.