Under the terms of a Company Voluntary Agreement (CVA), Focus will give landlords of its empty stores two lump-sum payments equivalent to six months' rent and will also cover rates bills.
Focus will pay rent monthly rather than quarterly on stores that are open.
Three-quarters of creditors backed the plan.
At a creditors' meeting on 24 August, plans to save Focus won between 93% and 100% backing from landlords. The move means that Focus will pay its creditors a proportion of what it owes them.
Focus chief executive Bill Grimsey said: "We are very pleased. Trading is currently ahead of management expectations and with this CVA now firmly behind us we can concentrate on managing our existing open stores and building on this stable platform to offer the best service to all our customers, suppliers, employees and landlords."
The DIY and gardening chain is still trading from 180 stores, but its 38 closed outlets are costing it £12m a year in rent and Focus has said this financial drain "threatens the immediate future of the core business".
Subscribe to Horticulture Week for more news, more in-depth features and more technical and market info.