Fulham Palace Garden Centre closes on 31 August with no new tenant in place to take over after Pets at Home pulled out of a deal to lease the site following local opposition.
The site belonging to a trading arm of the charity the Prince’s Trust will be empty by 1 September after a "crazy" closing down sale.
A staff member told HW: "We were told Pets at Home had pulled out last week and 10 of us have been made redundant."
She said the centre was almost empty with just a few plants left to sell after a "crazy" sale. Local protests against Pets at Home preceded the company’s withdrawal.
A Prince’s Trust representative said: ""As a charity, The Prince’s Trust is required to focus on its core activity of supporting disadvantaged young people into jobs and training. The garden centre is not a core part of The Trust’s operations and, with this in mind, we are looking at leasing the site as this will be the best way to raise funds in support of more young people.
"The decision to close at the end of the month is based on the cycle of the store – we would have had to commit to substantial purchases of stock to stay open for the next phase. We are currently exploring options for the future of the centre, which is likely to be taken on by another business, and we are hoping to complete the process as swiftly as possible"
Meanwhile another London centre, Morden Hall, which closes in mid-September after the National Trust refused to extend Capital Gardens' lease, is also almost empty.
A member of staff said: "We have limited stock left. We’re not sure when we’re closing but it will be mid-September we think. It will continue as a garden centre under new management by the National Trust."
No-one at the National Trust was available to respond to questions about the future of the site.