Dobbies regional manager Nick Anderson said: "We’re really looking forward to coming to Cambridge and are currently recruiting for 14 great people to join us.
"Gardening enthusiasts should visit our website to find out about the full range of opportunities.
"We’ll be recruiting experts in horticulture and experts in pets."
Dobbies plans to open on October 3.
Meanwhile, Edinburgh Woollen Mill plans to open a concession at Dobbies Dunfermline.