Glyphosate re-registration was delayed by the EU for a second time this month. Registration runs out at the end of June.
Monsanto business director Gary Philpotts said: "I'm disappointed that we haven’t yet had a decision, but understand the Commission’s desire to get as many Member States on board as possible, although there are still a number of options still open to the Commission.
"Some Member States still have concerns, but the evidence in support of re-approval is clear, unambiguous and supported by regulatory authorities around the world, not just here in Europe.
"Failure to re-approve glyphosate would have significant negative repercussions for the competitiveness of European agriculture, horticulture, the environment, and the ability of farmers to produce safe and affordable food.
"In the existing EU legislation, the Commission cannot simply run out the clock on approval without leaving itself open to serious legal challenge. The Commission has a legal obligation to take a decision on re-approval."
The European Parliament’s environment, public health, and food safety committee (ComEnvi) held a hearing on May 24 on the EU's approval process for glyphosate but have yet to agree on a vote.
Several countries including Malta have stated they will vote against renewal.