The new role will report directly to Paul Loft, Homebase’s managing director.
She joins from Start, the charity initiative, where she is CEO. She replaces Ajay Kavan who left the business earlier in the year.
Loft said: "The customer is, and always will be, at the forefront of Homebase’s activities. We aim to lead the march on ideas and inspiration in the home and garden".
He added: "Jo’s background in FMCG, retailing and at Start is ideally placed to move us on to the next step in the Homebase journey.
Kenrick said: "I'm delighted to be joining the team at Homebase - I've always believed that women were the key decision makers in Home Improvement and this is a business which already has a strong female franchise. There is so much already in place to build on and a great team with which to do it so I'm really looking forward to getting started".
She started her career at Mars and PepsiCo, and she has operational, sales and marketing experience in both fast moving consumer goods (FMCG) and retail. More recently, she was marketing and customer proposition director at B&Q.