The sci-fiesque landscape in Cornwall defined by translucent biomes is one of seven places shortlisted for the award that goes to public vote.
The announcement is one piece of good news for horticultural attractions across the board hit by wet and torrid weather.
Rain has kept visitors away from gardens and stately homes across the country, with Batsford Arboretum in Gloucestershire the latest to report hard times caused by downpours. Visitor numbers dropped 13 per cent on last year thanks to an awful April and dank summer.
Eden sales and marketing director Martin Williams said: "We are proud to be nominated for the 2012 award, particularly after winning last year.
"With new additions such as the SkyWire, a 640m zipwire offering a bird’s eye view of the biomes, we always develop fresh ideas."
Since opening in 11 years ago, nearly 14m people have visited Eden, which has generated £1.2bn for the local economy.
Capital funding to develop Eden has come from lottery sources, the now-defunct South West Regional Development Agency, European funds and loans.
The British Travel Awards, often hailed as the Oscars of the holiday industry, are the largest of their kind in the UK with 75 types of holiday experiences, including destinations, accommodation and customer care clocking up tens of thousands of votes.
A panel of travel industry professionals narrowed down the nominations for this year’s gong and people have until 30 September to vote for the best UK leisure attraction and other categories.
Other nominees in the same category include Longleat Safari Park, the Minack Theatre and Madame Tussauds. Winners will be announced at an award ceremony in London on 1 November.
To vote go to http://britishtravelawards.com/vfp.php