Britain's Great Garden Festival will be part of the show, which runs from July 8 to the 13, and is a competition which tasks gardeners to design a 12m by 12m garden, which celebrates where they live. The winner will get the opportunity to work with top designer Adam Frost.
Entrants will need to think of ways to reflect their community's heritage, buildings, foods, people or plants or other aspects of their local life. Judges will be looking for originality and good use of plants.
The closing date for entries is midday on March 24. Judges will select the three most promising amateur designers, who will then compete against each other for the grand prize - an opportunity to work with professional mentors to create their garden in time for the RHS Hampton Court Palace Flower Show in July.
The two mentors, The One Show gardener Christine Walkden and RHS Chelsea Flower Show Gold medal-winning designer Adam Frost, will teach them more about plants, garden design and landscaping, and then will help them create The One Show Garden at the RHS Hampton Court Palace Flower Show.
RHS Hampton Court Palace Flower Show manager Dave Green said: "This is a fantastic opportunity for someone passionate about gardening and design to learn from one of the UK's top garden designers and best loved plantswomen. The winner's journey to bring the garden to life at one of Britain's most popular gardening shows will be challenging, inspirational and rewarding."
Last year attracted hundreds of designs, according to The One Show's deputy editor Michael Armit.
He added: "The garden has also more than doubled in size so the stakes are even higher. The judges are going to be looking for something very special to create impact and make the best use of the larger space."